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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FSHR
All Species:
30.3
Human Site:
S295
Identified Species:
83.33
UniProt:
P23945
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23945
NP_000136.2
695
78295
S295
L
H
P
I
C
N
K
S
I
L
R
Q
E
V
D
Chimpanzee
Pan troglodytes
XP_525753
695
78196
S295
L
H
P
I
C
N
K
S
I
L
R
Q
E
V
D
Rhesus Macaque
Macaca mulatta
XP_001114171
695
78240
S295
L
H
P
I
C
N
K
S
I
L
R
Q
E
V
D
Dog
Lupus familis
XP_538488
692
78161
S295
L
H
P
I
C
N
K
S
I
L
R
R
E
I
E
Cat
Felis silvestris
Mouse
Mus musculus
P35378
692
77751
S295
L
H
P
I
C
N
K
S
I
S
R
Q
D
I
D
Rat
Rattus norvegicus
P20395
692
77663
S295
L
H
P
I
C
N
K
S
I
L
R
Q
D
I
D
Wallaby
Macropus eugenll
Q6YNB6
694
78462
S295
L
H
P
I
C
N
K
S
F
V
R
Q
D
S
D
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79763
693
78680
S295
F
Y
P
I
C
S
M
S
P
A
K
Q
D
L
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001001812
668
75168
S281
Q
A
N
L
T
Y
P
S
H
C
C
A
F
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
96.8
91.3
N.A.
87.7
89.6
81.2
N.A.
73.2
N.A.
53.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
98.2
95.8
N.A.
92.6
93.9
89
N.A.
83.4
N.A.
71.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
80
86.6
73.3
N.A.
33.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
86.6
N.A.
66.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
0
0
0
0
12
0
12
0
0
0
% A
% Cys:
0
0
0
0
89
0
0
0
0
12
12
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
45
0
67
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
45
0
12
% E
% Phe:
12
0
0
0
0
0
0
0
12
0
0
0
12
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% G
% His:
0
78
0
0
0
0
0
0
12
0
0
0
0
0
0
% H
% Ile:
0
0
0
89
0
0
0
0
67
0
0
0
0
34
0
% I
% Lys:
0
0
0
0
0
0
78
0
0
0
12
0
0
12
0
% K
% Leu:
78
0
0
12
0
0
0
0
0
56
0
0
0
12
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
0
0
78
0
0
0
0
0
0
0
0
12
% N
% Pro:
0
0
89
0
0
0
12
0
12
0
0
0
0
0
0
% P
% Gln:
12
0
0
0
0
0
0
0
0
0
0
78
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
78
12
0
0
0
% R
% Ser:
0
0
0
0
0
12
0
100
0
12
0
0
0
12
0
% S
% Thr:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
12
0
0
0
34
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
12
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _